Biguanides
Metformin (Glucophage, Diaformin, Diabex) Metformin extended release (Diabex XR)
Dose
Metformin: usually taken twice a day with breakfast and evening meals
Metformin extended release: usually taken once a day in the morning.
Take with food to minimize symptoms.
Effect
Works by decreasing the amount of glucose released from liver and by making cells more sensitive to insulin.
Side effect
Include bloating, gas, diarrhea, upset stomach, loss of appetite (usually within the first few weeks of starting).
Other note: Always tell healthcare providers that it may need to be stopped when you having a surgical procedure.